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Program

Arrival and Introduction

Time Program
8:30–8:50 Arrival
8:50–9:00 Introduction

Session 1: 9:00-10:30

Time Program Speaker Title
9:00-9:35

Talk

Prof. Dr. Martin Pacesa Computational design: what we can and cannot do, and why
9:35-10:10 Talk

Prof. Dr. Weixin Tang

Precision and Specificity in Therapeutic Base Editing

10:10-10:25 Short Talk Dr. Charles Yeh Searching for similarities: homology search in DNA repair & CRISPR/Cas9 genome editing

Coffee break: 10:30-11:00

Session 2: 11:00-12:30

Time Program Speaker Title
11:00-11:35 Talk Prof. Dr. Dominic Hoepfner From Screens to Targets: Leveraging CRISPR in complex in vitro models for tendon repair and kidney disease
11:35-12:10 Talk Prof. Dr. Julian Grünewald

Gene editing for heart disease

12:10-12:25

Short Talk Dr. Andras Talas In vivo rescue of a urea cycle disorder via RNA-LNP-mediated prime editing

Lunch on your own: 12:30-13:30 Location information

Session 3:  13:30–15:10

Time Program Speaker Title
13:30-14:05 Talk Prof. Dr. Tommaso Cavazza  Errors at the beginning of life: aneuploidy and mammalian embryogenesis 

14:05-14:40

Talk Prof. Dr. Jack Bravo Beyond CRISPR: Argonaute-mediated self/non-self discrimination in bacterial defense
14:40-14:55 Short Talk Friso Schut RNA-triggered cell killing with Cas12a2
14:55-15:10 Short Talk Dr. Tanmay Tanna Enhanced transcriptional recording sentinel cells enable clinically relevant in vivo sensing in the gut

Coffee break: 15:10–15:40 

Session 4: 15:40–17:15

15:40-16:15 Talk

Prof. Dr. med. Soeren Lienkamp

Pythia: Precise, predictable genome integrations and edits by deep-learning assisted design of microhomology-based templates
16:15-16:50 Talk Prof. Dr. Jonathan Schmid-Burgk  Pooled experiments for studying sub-cellular signal processing
16:50-17:05 Short Talk Seraina Oberli and Dr. Giada Finocchio  

Structural basis of RNA-guided DNA integration by type I CRISPR-associated transposases

17:05-17:15 Closing remarks